Brains meaning : The control center of the central nervous system of an animal located in the skull which is responsible for perception, cognition, attention, memory, emotion, and action. An intelligent person. (in the plural) Intellect. By analogy with a human brain, the part of a machine or computer that performs calculations. Oral sex. Mind. To dash out the brains of; to kill by smashing the skull. To strike (someone) on the head. To destroy; to put an end to. To conceive in the mind; to understand. The substance of a brain as a material or foodstuff. The figurative substance of a brain: mental ability, intelligence. (with 'the') The intelligent person or people in a group: the director, planner, administrator, &c.