Twang meaning : The sharp, quick sound of a vibrating tight string, for example, of a bow or a musical instrument. A particular sharp vibrating sound characteristic of electric guitars. A trace of a regional or foreign accent in someone's voice. The sound quality that appears in the human voice when the epilaryngeal tube is narrowed. A sharp, disagreeable taste or flavor. To produce or cause to produce a sharp vibrating sound, like a tense string pulled and suddenly let go. To have a nasal sound. To have a trace of a regional or foreign accent. To play a stringed musical instrument by plucking and snapping.